PubMed: Szakterületek: This study aims at evaluating the prevalence of left ventricular diastolic dysfunction in a group of hypertensive patients with stage 3b chronic kidney disease according to Kidney Disease Improving Global Outcomes classificationcompared with patients with essential hypertension and normal renal function. All patients underwent echocardiographic examination.
Patients on stage a chronic kidney disease, dialysis treatment, or with previous manifestations of heart failure or other cardiovascular diseases were excluded. Patients with renal disease had significantly worse diastolic function both considering trans-mitral flow and tissue Doppler imaging parameters.
Diastolic dysfunction is found in Multiple regression analysis shows an association essential hypertension classification renal function and diastolic function beta 0. Our study shows that diastolic dysfunction is highly prevalent in patients with advanced chronic kidney disease; we posit that in this population, the risk of diastolic heart failure is very high.
We think that patients with a marked decrease of glomerular filtration rate GFR must be considered at high risk essential hypertension classification diastolic heart failure and should have an echocardiographic examination performed, even if asymptomatic and in the absence of evident cardiovascular disease.